Foot Disorders in X-linked Hypophosphatemia

Orthopedic Hospital Vienna Speising28 enrolled

Overview

This study aimed to characterize foot pathologies using X-rays and clinical examination and assess related outcome scores in adolescents and adults with X-linked Hypophophatemia

A single center, cross-sectional analysis of adolescent and adult patients with XLH with and without previous surgical intervention was performed at the Orthopaedic Hospital Speising, Vienna, Austria. Clinical examination, quality of life questionnaires and radiographic data of foot x-rays in standing position were collected. Radiographic evaluation was performed to analyze foot deformity as well as signs of osteoarthritis at the foot.

Study Type

OBSERVATIONAL

Enrollment

Conditions

X-linked Hypophosphatemia

Interventions

Foot X raysRADIATION

Radiographs of ankle and foot anteroposterior/dorsoplantar were taken in standing position with a centralized beam on the ankle joint.

Clinical examination + scoresDIAGNOSTIC_TEST

The American Orthopedic Foot and Ankle Society Score (AOFAS- midfoot section and 1st Forefoot ray, Forefoot ray 2-5) and the foot function index (FFI) were assessed

Eligibility

Sex: ALLMin age: 16 YearsMax age: 100 Years

Medical Language ↔ Plain English

Inclusion Criteria: - Patients with confirmed XLH, ≥ 16 years were invited to participate in this study Exclusion Criteria: * Exclusion criteria were other forms of hypophosphatemia, pregnancy and recent lower limb surgery within 3 months.

Locations (1)

Orthopedic Hospital Speising Vienna

Vienna, Austria

Outcomes

Primary Outcomes

Number of feet with signs of osteoarthritis

radiographic signs of osteoarthritis at the foot joints

Time frame: baseline

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.