Bowel urgency is commonly defined as the sudden need to rush to the bathroom to empty one's bowel. In the field of inflammatory bowel disease (IBD) (including Crohn's disease (CD) and ulcerative colitis (UC)), bowel urgency is part of the top five research priorities for future IBD nursing research, and it is a symptom that patients consider to be most important when prioritizing their disease control. Urgency is a patient-reported outcome associated with compromised quality of life and future risk of hospitalizations, corticosteroids, and colectomy in patients with UC. A meta-analysis of 321 studies examining bowel urgency revealed that only one-third of these clinical studies clearly defined the concept of bowel urgency. Definition of bowel urgency was heterogeneous as 14 different definitions were identified. In most of these studies, non-validated questionnaires were used. They are based on subjective responses of the patients, and they could determine evaluation bias. These data emphasize the lack of standardization in bowel urgency assessment.
Study Type
OBSERVATIONAL
Enrollment
1,000
Data will be extracted from the patient's medical record and patients will be interviewed to collect data specific to the research
Institut des MICI
Neuilly-sur-Seine, France
Prevalence of bowel urgency in a cohort of patients with inflammatory bowel disease
Inability to defer defecation for more than 15 minutes in patients with inflammatory bowel disease
Time frame: Through study completion, an average of 12 months
Prevalence of bowel urgency in a cohort of Crohn's disease patients
Inability to defer defecation for more than 15 minutes in patients with Crohn's disease
Time frame: Through study completion, an average of 12 months
Prevalence of bowel urgency in a cohort of ulcerative colitis patients
Inability to defer defecation for more than 15 minutes in patients with ulcerative colitis
Time frame: Through study completion, an average of 12 months
Development of the URGENT index (i.e. inflammatory bowel disease-specific bowel urgency index)
Components of the index based on variables describing in systematic review Caron B et al. Clin Gastroenterol Hepatol. 2023 and IBD expert opinion
Time frame: Through study completion, an average of 12 months
To identify IBD-related risk factors associated with an increased risk of bowel urgency
Inability to defer defecation for more than 15 minutes and potentially predictive factors (i.e. baseline characteristics)
Time frame: Through study completion, an average of 12 months
Correlation between the URGENT index and the Urgency Numeric Rating Scale
Relationships between changes in the URGENT index and changes in the Urgency Numeric Rating Scale
Time frame: Through study completion, an average of 12 months
Correlation between the URGENT index and a Global Visual Evaluation
Relationship between changes in the URGENT index and changes in the Global Visual Evaluation on a 10-point visual analog scale ranging from 0 (minimal activity) to 10 (maximal activity)
Time frame: Through study completion, an average of 12 months
Most appropriate definition of bowel urgency for patients with IBD
Urgent desire to defecate and/or extreme desire to defecate and/or immediate need to defecate and/or inability to defer defecation for more than 2 minutes and/or inability to defer defecation for more than 5 minutes and/or inability to defer defecation for more than 20 minutes and/or inability to defer defecation for more than 30 minutes and/or having to rush to the toilet and/or not making it to a toilet in time and/or having to stop whatever to have a bowel movement and/or difficult to withstand urge to open bowels and/or running to the bathroom and/or inability to delay bowel movements
Time frame: Through study completion, an average of 12 months
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