ChAracterization of Normal and Pathological moRphological Variations of the TEMporomandibular Joint by Real-time magnetIc reSonance Imaging

N/ANot Yet RecruitingNCT06070558

Central Hospital, Nancy, France60 enrolled

Overview

The Real Time MRI Rapid Flash sequence is particularly interesting for the study of moving organs and joints. This sequence will make it possible to characterize normal and pathological temporomandibular joint movements by MRI.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

OTHER

Masking

NONE

Enrollment

Conditions

Healthy Temporomandibular Joint Disorders

Interventions

MRI with Real Time MRI Rapid Flash sequenceDEVICE

MRI examination of temporomandibular joint with Real Time MRI Rapid Flash sequence

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Adult: age ≥ 18 years old; * Person with the capacity to understand the instructions given; * Person affiliated to a social security scheme or beneficiary of such a scheme; * Person having received complete information on the organization of the Clinical Investigation and having signed informed consent. Exclusion Criteria: * Person with large-scale metallic dental reconstructions; * Edentulism more than 5 teeth; * Claustrophobia; * Contraindication to performing an MRI examination * Persons referred to in Articles 64, 65 and 66 of European Regulation 2017/745 on Medical Devices (RDM) and in L. 1121-5 to L1121-8 of the French Public Health Code

Locations (1)

CHRU de Nancy

Nancy, France

Outcomes

Primary Outcomes

Curve representing the difference between displacement of condyles during Temporo Mandibular Joint (TMJ) movements in healthy subjects and in subjects with known Temporo Mandibular Disorder (TMD).

Time frame: Baseline (day 0)

Secondary Outcomes

Curve representing the displacement of the articular discs during TMJ movements

Time frame: Baseline (day 0)

Curve representing the difference between displacement of joint discs during TMJ movements in healthy subjects and in subjects with known TMD

Time frame: Baseline (day 0)

Characterization of the volume in mm3 of the main masticatory muscles during movement by MRI in healthy and pathological subjects.

Time frame: Baseline (day 0)

Central Contacts

Pedro Augusto GONDIM TEIXEIRA, MD, PhD

CONTACT

0033 3 83 85 21 61 p.teixeira@chru-nancy.fr

Gabriela Hossu, PhD

CONTACT

0033 3 83 15 50 96

Data from ClinicalTrials.gov

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