The purpose of the project is to investigate exercise performance in humans following prolonged inhalation of beta2-agonists vilanterol + fluticasone furoate or indacaterol + mometasone furoate
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Enrollment
60
Participants inhale 25 µg vilanterol + fluticasone furoate daily
Participants inhale 125 µg indacaterol + mometasone furoate daily
Participants inhale placebo daily
August Krogh Building
Copenhagen, Denmark
RECRUITINGExercise capacity during a time trial
Mean power output measured in Watts during a time trial on a bike ergometer
Time frame: Through study completion, an average of 8 weeks
Lung function
Forced expiratory volume in 1 second (FEV1) measured by spirometry before and after time trial with and without beta2-agonist induced bronchodilation
Time frame: Through study completion, an average of 8 weeks
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