Different Doses of Colchicine on hsCRP

Inclusion Criteria: 1. Volunteer to participate, understand and sign an informed consent form; 2. Age ≥ 18 years old, regardless of gender; 3. Patient diagnosed with coronary heart disease requiring percutaneous coronary intervention; 4. Complete all planned percutaneous coronary intervention during hospitalization; 5. Patient must be treated according to national guidelines for standard treatment of coronary heart disease. Exclusion Criteria: 1. Known allergies to colchicine; 2. Colchicine was taken within 10 days before randomization; 3. Abnormal liver function test (alanine aminotransferase \>3 times the upper limit of normal value); 4. Abnormal renal function test (eGFR\<30mL/min); 5. Thrombocytopenia (platelet count \<100 g/L); 6. Uncontrolled infectious diseases; 7. Known immune diseases or immune-related diseases such as systemic lupus erythematosus, asthma, inflammatory bowel disease, gout, and malignant tumor, etc; 8. Pre-existing or plan for the administration of nonsteroidal anti-inflammatory drugs, hormones, immunomodulatory drugs, or chemotherapeutic drugs; 9. Pregnant women, lactating women or women of childbearing age who do not use effective contraceptives; 10. Any other circumstances in which the investigator judges that the patient is not suitable to participate in the clinical trial.