Prevention of Shivering Associated With Spinal Anesthesia

Phase 3UnknownNCT06082076

Assiut University90 enrolled

Overview

The aim of the study is to compare the effectiveness of prophylactic use of intravenous (IV) dexmedetomidine VS ketamine and meperidine(as a control group) in prevention of shivering associated with intrathecal anesthesia in patients undergoing knee arthroscopy

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Shivering, Spinal Anesthesia

Interventions

DexmedetomidineDRUG

Patients will receive dexmedetomidine 0.5 mcg/kg diluted in 10 mL of NS given as IV infusion over 10 min before induction of spinal anesthesia

KetamineDRUG

Patient will will receive ketamine 0.5 mg/kg diluted in 10 mL of NS given as IV infusion over 10 min before induction of spinal anesthesia

MeperidineDRUG

If the tested drug hasn't stopped shivering patient will receive 0.25 mg/kg meperidine

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: \- BMI 20-30 Scheduled patients for knee arthroscopy under spinal anesthesia. American Society of Anesthesiologists (ASA) physical status: I and II Exclusion Criteria: * Patient refusal Aged less than 18 years or lesser than 150 cm in height Pregnant woman Allergy to the studied drugs. Patients with contraindications to spinal anesthesia. Patients with advanced decompensated cardiac, respiratory,renal or hepatic diseases, ASA III-IV Coagulopathy or thrombocytopenia CNS diseases as epilepsy, stroke or psychiatric illness.

Outcomes

Primary Outcomes

Incidence of shivering

Incidence of shivering post intrathecal anesthesia is recorded

Time frame: During operation time

Central Contacts

Ahmed Ga Mohammed, Resident

CONTACT

+201091339220 ahmedgalalm678@gmail.com

Data from ClinicalTrials.gov

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