Immediate Loading of 4 Guided Implants Supporting a Maxillary Overdenture Using a Novaloc TiN Retention System

Inclusion Criteria: * Fully edentulous maxilla * The implant site has to be healed for at least 4 months after extraction * Wearing complete dentures deemed adequate * Orthopantomogram available (OPT) * Adequate amount of bone at least at the 2nd premolar position to house a 3.75 x 10 mm implant * No bone grafting required * Implant IT ≥ 20 N/cm Exclusion Criteria: * Conditions requiring chronic routine prophylactic use of antibiotics * Conditions requiring prolonged use of steroids * History of leukocyte dysfunction and deficiencies * Bleeding disorders * History of neoplastic disease requiring use of radiation or chemotherapy * Metabolic bone disorders * Uncontrolled endocrine disorder * Use of any investigational drug or device within the 30-day period prior to implant surgery * Smoking more than 10 cigarettes a day * Alcoholism or drug abuse * Patient infected with HIV * Condition or circumstances, in the opinion of the investigator, which would prevent completion of study participation or interfere with analysis of study results, such as history of non-compliance, unreliability. Local exclusion criteria: * Local inflammation including untreated periodontitis * Mucosal disease such as erosive lichen planus * History of local irradiation therapy * Osseous lesion * Severe bruxism and clenching habits * Active infection with suppuration or fistula track * Persistent intraoral infection * Lack of primary stability \<20Ncm. In this instance, the patient must be withdrawn and treated according to the standard protocol. * Inadequate oral hygiene or unmotivated home care. * Bone grafting * Inadequate bone volume for implants insertion as measured on the per-treatment CBCT.