NCT06086483 - Pain Management After Adductor Canal Block for Total Knee Arthroplasty | Crick

Overview

This randomized, double-blinded, placebo-controlled trial sought to evaluate the efficacy of the iPACK block with Adductor Canal Block on postoperative pain, functional recovery and NLR and PLR levels.

The Interspace between the popliteal artery and capsule of the posterior knee, or iPACK block, together with the Adductor Canal block (ACB), has been described and shows promise in providing analgesia to the knee joint. However, the effect of these two blocks on postoperative pain levels, functional recovery, and stress response is uncertain. This study compares a preoperative iPACK and ACB block to Sham blocks before total knee arthroplasty under spinal anesthesia.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

361

Conditions

Knee Osteoarthritis Knee Arthritis Knee Arthropathy Knee Pain Chronic

Interventions

Ropivacaine 0.2% Injectable SolutionDRUG

20 mL 0.5% ropivacaine was injected into the PENG block 20 mL 0.5% ropivacaine was injected into the Adductor Canal block

0.9%sodium chlorideDRUG

20 mL 0.9% sodium chloride was injected into the PENG block 20 mL 0.5% sodium chloride was injected into the Adductor Canal block

Eligibility

Sex: ALLMin age: 18 YearsMax age: 100 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients \> 18 years old undergoing unilateral total knee arthroplasty Exclusion Criteria: * refusal to participate * \< 18 yo * Chronic opioid use * localized infection

Locations (1)

Poznan University of Medical Sciences

Poznan, Poznań, Poland