This study will test the feasibility and effectiveness of an innovative model of care for cognitively impaired patients with heart failure. This program aims to improve cognition, reduce dementia risk and cardiovascular events, and will be supported by innovative digital technology for wide scale rollout and implementation. Findings from this research will transform the way healthcare is delivered to cognitively impaired patients with heart disease who have a very high risk of developing dementia.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
168
The components of our DMP include: 1. Intensive post-discharge education 2. Home surveillance of signs and symptoms will be reviewed (weekly in the first month and monthly thereafter) in a telehealth consultation with patient and/or carer. 3. Medical treatment involves a planned up-titration of cardioprotective medications that will proceed in the absence of advice from the general practitioner (GP) to the contrary. Close observation and frequent appointments are organised by the nurse with the patient's GP during up-titration period. 4. Exercise program delivered by an exercise physiologist 5. Maintenance phase of the DMP: During this maintenance phase, Intervention patients should have been fully transitioned to home care where they are managed by their GP at optimal doses of their medications. Repeated education and exercise guidance will continue with the carer, supported by our cardiac nurse and exercise physiologist via telehealth consultation bimonthly.
Menzies Institute for Medical Research
Hobart, Tasmania, Australia
RECRUITINGChange in MOCA score
Greater Montreal Cognitive Assessment (MOCA) score (ranging 0-30) is better
Time frame: 12 months
Change in cardiac function
Cardiac function will be measured by echocardiography. Left ventricular global longitudinal strain will be the primary measure of cardiac function.
Time frame: 12 months
Change in 6-minute walk distance
Functional capacity will be based on 6-minute walk test
Time frame: 12 and 24 months
Change in quality of life
Quality of life specific to heart failure symptoms will be measured using a disease-specific quality of life questionnaire: Kansas City Cardiomyopathy Questionnaire
Time frame: 12 and 24 months
Change in MOCA score
Greater Montreal Cognitive Assessment (MOCA) score (ranging 0-30) is better
Time frame: 24 months
Change in brain volume via MRI measurement
Time frame: 24 months
Change in hand grip strength
Time frame: 12 and 24 months
Change in heart failure classification
Based on New York Heart Association classification
Time frame: 12 and 24 months
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