Belgian Registry on Coronary Function Testing

University Hospital, Antwerp650 enrolled

Overview

The goal of this prospective, multicenter registy is to describe the 'real-world' use of coronary function tests, which may consist of bolus thermodilution measurements of coronary microvascular function and/or invasive vasoreactivity tests with acetylcholine, in the current Belgian routine practice. The main questions it aims to answer are: * how frequent are coronary function tests performed * what is the indication for coronary function tests * what is the frequency of coronary microvascular dysfunction * what is the frequency of coronary artery vasospasm From each participant, data will be collected from their medical files concerning cardiovascular risk factors, relevant past medical history, non-invasive tests, procedural data, and follow-up data from routine in-patient visits. Their are no specific study visits. Optionally, patients will be asked to fill in questionnaires about anginal symptoms and quality of life.

Study Type

OBSERVATIONAL

Enrollment

650

Conditions

Coronary Microvascular Dysfunction Coronary Artery Vasospasm

Interventions

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patient scheduled for coronary function test, comprising of intracoronary bolus thermodilution measurements of microvascular function, and/or intracoronary vasoreactivity tests with acetylcholine. * Subject understands the study requirements and provides written informed consent. Exclusion Criteria: * Subject is participating in another investigational clinical trial that may cause non-compliance with the protocol or confound data interpretation. * Subject intends to participate in another investigational clinical trial that may cause non-compliance with the protocol or confound data interpretation. * Documented or suspected pregnancy. * Inability to provide written informed consent.

Locations (13)

AZ Monica

Deurne, Antwerp, Belgium

RECRUITING

AZ Sint-Maarten

Mechelen, Antwerp, Belgium

RECRUITING

Jessa Hasselt

Hasselt, Limburg, Belgium

RECRUITING

OLV Aalst

Aalst, Belgium

RECRUITING

Ziekenhuis aan de Stroom (ZAS)

Antwerp, Belgium

RECRUITING

University Hospital Antwerp

Antwerp, Belgium

RECRUITING

AZ Sint-Jan Brugge

Bruges, Belgium

RECRUITING

AZ Jan Yperman

Ieper, Belgium

RECRUITING

AZ Groeninge

Kortrijk, Belgium

RECRUITING

UZ Leuven

Leuven, Belgium

RECRUITING

...and 3 more locations

Outcomes

Primary Outcomes

Frequency of coronary microvascular dysfunction and/or coronary artery vasospasm

To measure the frequency of coronary microvascular dysfunciton coronary artery and vasomotor disorders among patients undergoing coronary function tests.

Time frame: 5 years

Secondary Outcomes

Describe predictors for coronary microvascular dysfunction and/or coronary artery vasospasm

To find predictors for coronary microvascular dysfunction and/or coronary artery vasospasm by means of multivariate regression analysis.

Time frame: 5 years

Describe 1- year and 3-year MACE among the different endotypes of coronary microvascular dysfunction with/whithout coronary artery spasm.

To describe the difference in 1-year and 3-year MACE between the different endotypes of coronary microvascular dysfunction obtained.

Time frame: 5 years