The Eye in Orbit: UCF Adaption

University of Central Florida1 enrolled

Overview

The goal of this study is to understand the impact of space travel on the eyes. Space flight impacts numerous aspects of ocular anatomy and physiology. Current hypotheses are based on pressure changes within and around the optic nerve. Retinal and choroid blood drainage may be affected by microgravity associated cerebrospinal fluid pressure changes. Recently, a new imaging modality, Optical Coherence Tomography Angiography (OCTA), has been able to reveal micro vascular changes in the retina and choroid. To date, no microgravity ocular imaging tests have been published using OCTA. In this study the researchers aim to describe microgravity circadian choroidal and retinal vasculature using multimodal imaging including OCTA to better understand space associated ocular changes.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Spaceflight Associated Neuro-Ocular Syndrome SANS

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: \- astronauts in the AX1/Rakia mission, which was scheduled for space flight in late March 2022. Exclusion Criteria: * adults unable to consent * individuals who are not yet adults (infants, children, teenagers) - * pregnant women * prisoners.

Locations (1)

Outcomes

Primary Outcomes

To examine early changes in ocular physiology following exposure to microgravity and asses these changes as risk factor for Spaceflight Associated Neuro-Ocular Syndrome (SANS).

Time frame: 4 months

Asses early changes in ocular physiology as risk factor for Spaceflight Associated Neuro-Ocular Syndrome (SANS).

Time frame: 4 months