A Study in Subjects With Liver Function Injury and Subjects With Normal Liver Function

Inclusion Criteria: 1. On the day of signing the informed consent form, the age range is 18 to 70 years (including both ends), both male and female are eligible; 2. Male subjects weighing no less than 50 kg and female subjects weighing no less than 45 kg; Body mass index (BMI) 18-32 kg/m2 (including both ends), where BMI=weight (kg)/height 2 (m2); Subjects with normal liver function also need to meet all the following conditions: 3. When screening, the following demographic matching criteria must be met: 1. Match the weight with the liver function impairment group, with a mean of ± 10 kg; 2. Age matched with the liver function impairment group, with a mean of ± 10 years; 3. Gender matching was performed with the liver function impairment group, with a mean of ± 1 case; Subjects with liver function impairment also need to meet all the following conditions: 4. Patients with chronic liver injury caused by primary liver diseases (such as hepatitis B, hepatitis C, autoimmune hepatitis, alcoholic liver disease, etc.) and stable liver function (without any liver disease related medical records within 14 days before taking the study drug, except for regular follow-up and medication) with liver dysfunction classified as A or B by Child-Pugh ; 5. Clinically diagnosed as liver cirrhosis; 6. Those who have a stable medication plan for the treatment of liver function damage, complications, and other accompanying diseases for at least 14 days before taking the study drug, and the medication does not need to be adjusted (including medication type, dosage, or frequency); Or those who have not taken medication; 7. Estimated Glomerular filtration rate (eGFR, calculated using the CKD-EPI formula) ≥ 60 mL/min/1.73m2; Exclusion Criteria: 1. The electrocardiogram shows a QTc interval (QTcF) of\>450 msec for males and\>470 msec for females (corrected according to Fridericia's standard); 2. Screening for individuals with severe infections, trauma, gastrointestinal surgery, or other major surgical procedures within the first 4 weeks; 3. Those who have received the vaccine within 14 days before screening or plan to receive the vaccine during the study period; 4. Those who donate blood or have a blood loss of ≥ 400 mL within the first 3 months of screening, or intend to donate blood during or within 1 month after the trial; 5. Screening for potent inhibitors or inducers of Pg-P or BCRP that have been used within the previous month (see Attachment 4); 6. Those who have taken a special diet (including dragon fruit, mango, grapefruit, and/or xanthine diet, chocolate) and/or consumed excessive amounts of tea, coffee, grapefruit/grapefruit juice, and/or caffeinated beverages (an average of 8 or more cups per day, 200 mL per cup) within 2 weeks before administration; 7. Screening for alcoholics within the first three months, i.e. those who consume more than 14 units of alcohol per week (1 unit=360 mL of beer, or 45 mL of 40% alcohol or 150 mL of wine) or those who are positive for alcohol screening; 8. Individuals who smoke an average of 10 or more cigarettes per day within the first 3 months of screening; Subjects with normal liver function who meet any of the following exclusion criteria need to be excluded: 9. History of liver injury; 10. Individuals who have previously or currently suffered from any clinical serious diseases such as circulatory system, endocrine system, nervous system, digestive system, respiratory system, hematology, immunology, psychiatry, and metabolic abnormalities, or any other diseases that may interfere with the test results; 11. Abnormalities in physical examination, vital signs, laboratory examination, 12 lead electrocardiogram, abdominal ultrasound, and other examinations have been determined by the researcher to have clinical significance; 12. Those who are positive in any index screening of hepatitis B surface antigen, hepatitis C antibody or hepatitis C core antigen, HIV antigen/antibody or syphilis antibody; 13. Have used any prescription drugs, over-the-counter drugs, Chinese herbal medicines, or supplements within 14 days prior to the administration of the study drug; Subjects with liver function impairment who meet any of the following exclusion criteria need to be excluded: 14. The subject has any of the following conditions: drug-induced liver injury; History of liver transplantation; And researchers believe that liver cirrhosis 15. During screening, the laboratory test results meet any of the following criteria: (a) alanine aminotransferase (ALT) or aspartate aminotransferase (AST)\>5 × ULN; (b) Absolute value of neutrophils (NE #)\<1 × 109/L; (c) Hemoglobin (HGB)\<80 g/L; (d) Alpha fetoprotein (AFP)\>100 ng/mL; 16. Except for the primary liver disease itself, those who have previously or currently suffered from other serious organ system diseases, including but not limited to gastrointestinal, respiratory, renal, neurological, hematological, endocrine, tumor, immune, mental, or cardiovascular diseases or clinical laboratory examination abnormalities, which have clinical significance, and are determined by the research doctor to be unsuitable for participating in this trial;