Study of Brain Function Evaluation System for Acute and Prolonged Disorders of Consciousness

Admission criteria for patients with prolonged disorders of consciousness Inclusion Criteria: 1. Age 14-60 years; 2. In accordance with the diagnostic criteria of unresponsive arousal syndrome or minimally conscious state by international research; 3. Brain Trauma, stroke and hypoxic-ischemic encephalopathy lead to disturbance of consciousness; 4. right-handed； 5. The patient's family members signed the informed consent form; Exclusion Criteria: 1. The history of mental illness and a history of hearing impairment; 2. Intracranial arterial clamp, pacemaker and other metal implants; 3. During the experiment, sedatives and other drugs that affect the excitability of the cortex; 4. The presence of uncontrolled seizures or involuntary movements; Admission criteria for patients with acute disorders of consciousness Inclusion Criteria: (1)Age 14-60 years; (2）Meets diagnostic criteria for coma recognized in international studies； (3)the GCS score was less than 8; (4)Brain Trauma, stroke and hypoxic-ischemic encephalopathy lead to disturbance of consciousness; (5) right-handed； (6)The patient's family members signed the informed consent form; Exclusion Criteria: 1. The history of mental illness and a history of hearing impairment; 2. Intracranial arterial clamp, pacemaker and other metal implants; 3. During the experiment, sedatives and other drugs that affect the excitability of the cortex; 4. The presence of uncontrolled seizures or involuntary movements; Admission criteria for patients with acute disorders of consciousness; 5. No spontaneous breathing; 6. Status Epilepticus; 7. Need emergency neurosurgical treatment can not cooperate with the examination;