Epigallocatechin Gallate and Other Antural Compounds in HPV Infections

Centro di Ricerca Clinica Salentino178 enrolled

Overview

The investigators enroll patients with a PAP-test cytology reporting LSIL or ASCUS. Pateitns undergo HPV-DNA test for screening. Patients are treated with Epigallocatechin galalte, hyaluronic acid, folic acid and Vitamin B12 by oral route. After three months of treatment PAP-test and HPV-DNA test will be repeated.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

178

Conditions

Papilloma-induced Cervical Lesions

Interventions

EGCG, FA, HA, B12DRUG

Epigallocatechin gallate 200mg, Hyaluronic acid 50mg, Vitamin B12 1mg, Folic acid 400mcg

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Positivity to HPV-DNA test * PAP-test reporting LSIL or ASCUS Exclusion Criteria: * HPV-related pathologies or complicances apart from LSIL or ASCUS * Diagnosis of cancer

Locations (1)

Ospedale Veris delli Ponti

Scorrano, Lecce, Italy

Outcomes

Primary Outcomes

Positivity to HPV infection

The outcome consists of the number of negative DNA-test obtained in patients previously positive.

Time frame: 3 and 6 months

Secondary Outcomes

Occurrence of lesions

The outcome consists of the number of negative PAP-tests obtained in patients previously positive.

Time frame: 3 and 6 months

Lesions-related symptmos

The ouctome includes the occurrence of bleeding, flogosis, or sexual pain.

Time frame: 3 and 6 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.