A Predictive Model for Early Metastasis in Cervical Cancer Patients After Radiotherapy

N/ANot Yet RecruitingNCT06101966

Fujian Cancer Hospital500 enrolled

Overview

This study aims to help to screen out appropriate cases for consolidation therapy and more intensive follow up.

Some cervical cancer patients experienced distant metastasis quickly after receiving complete radiotherapy and have a worse prognosis. However, there were few studies focused on these patients and with early distant metastasis. It is significant to predictive and screen out cervial cancer patients with a high risk of early metastasis for more comprehensive treatments and follow-up plans

Study Type

OBSERVATIONAL

Enrollment

500

Conditions

Cervical Cancer Radiotherapy Distant Metastasis Prognostic Model Risk Factor

Interventions

external pelvic beam radiotherapy (EBRT) followed by individualized high-dose-rate intracavitary brachytherapy (HDR-ICBT)RADIATION

Radical RT consisted of external pelvic beam radiotherapy (EBRT) and individualized high-dose-rate intracavitary brachytherapy (HDR-ICBT).Cisplatin-based concurrent chemoradiotherapy (CCRT) was recommended for CC patients unless for economic status, age consideration and patients' desires.

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients confirmed as cervical cancer by biopsies and treated with radiotherapy were initially enrolled Exclusion Criteria: * (1) patients treated with surgery. (2) patient received incomplete treatment somewhere else. (3) patients with cancer history. (4) patients with pelvic surgery history. (5) patients without complete pre-treatment medical information. (6) patients with unfinished radical radiotherapy. (7) patients suffered from metastasis within 3 months after radiotherapy. (8) patients without complete 1-year follow-up materials

Locations (1)

Fujian Cancer Hospital

Fuzhou, Fujian, China

Outcomes

Primary Outcomes

Early distant metastases

Early distant metastasis defines as metastasis occurrence between 3 -12 months after radiotherapy.

Time frame: 3-12months

Central Contacts

Yang Sun, PhD

CONTACT

+8615959028989 sunyang@fjzlhospital.com

Data from ClinicalTrials.gov

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