A Clinical Trial on the Treatment of Idiopathic Pulmonary Fibrosis

Inclusion Criteria 1. Females or males aged 40 to 80 (inclusive) at the time of signing the ICF; 2. Is willing to participate voluntarily in this clinical study and sign the ICF prior to study initiation; 3. Diagnosed with Idiopathic Pulmonary Fibrosis (IPF) according to the principles of the 2022 ATS/ERS/JRS/ALAT clinical practice guidelines; 4. Females or males of reproductive potential must agree and commit to using effective contraception from the time of signing the ICF until 90 days after the last dose of the investigational product; 5. Has stable anti-fibrosis treatment for at least 12 weeks prior to Visit 1. 6. FEV1/FVC ≥0.70 at screening; 7. Percent predicted forced vital capacity (% FVC) ≥45% and ≤90% at screening; 8. DLco% (Hb corrected) ≥30% and ≤90% at screening; 9. Is willing and able to comply with the protocol and attend visits as assessed by the investigator. Exclusion Criteria Subjects are not eligible for participation in the study if they meet any of the following exclusion criteria: 1. Patients with interstitial lung disease caused by other known aetiology; 2. Patients who experienced active tuberculosis infection within 12 months prior to screening, or present any bacterial, viral, parasitic, or fungal infection requiring treatment at screening; 3. Patients with IPF significantly worsened within one month prior to randomization; 4. Patients with range of emphysema more than that of pulmonary fibrosis as indicated by chest HRCT at screening; 5. Patients who are expected to undergo a lung transplant during the course of the study or have an expected survival of less than 1 year; 6. Patients who received any of the following medications within 28 days prior to randomization, such as unstable anti-fibrosis treatment, \>15 mg/d prednisone or equivalent dose of other glucocorticoids, immunomodulatory agents,strong inhibitors of CYP3A4; 7. Patients with a history of malignancy within 5 years prior to screening (except for patients with appropriately treated basal cell carcinoma of the skin or squamous cell carcinoma in situ of the skin or carcinoma in situ of the cervix); 8. Patients with moderate to severe hepatic insufficiency (Child-Pugh class B or C) prior to screening; 9. Patients with laboratory test results exceeding any of the following criteria at screening: total bilirubin \>1.5 x ULN or AST/ALT \>2 x ULN, and serum CK \>2.5 x ULN; 10. Patients with uncontrolled hepatitis B virus infection or hepatitis C virus infection at screening; 11. Patients with a history of unstable or worsening cardiac disease within 6 months prior to screening; 12. Patients with a family or personal history of long QT syndrome or QTcF \>480 ms at screening; 13. Patients with a creatinine clearance (CLcr) \<50 mL/min at screening, calculated using the Cockcroft-Gault formula; 14. Patients who are unable to complete the 6MWD test or PFT; 15. Pregnant or lactating women; Further exclusion criteria apply.