Prospective Ultrafast MRI Radiomics for Breast Cancer

Korea University Ansan Hospital225 enrolled

Overview

The goal of this prospective study is to investigate the performance of ultrafast MRI radiomics in classifying histological factors and subtypes of breast cancer compared with standard MRI among radiologists with varying experience. The written informed consent was obtained from all participant. We extracted 1618 radiomic features from ultrafast and standard contrast-enhanced MRI before treatment. Classification of hormonal receptors, human epidermal growth factor receptor 2, and Ki67 status and subtypes was evaluated using the area under the receiver-operating characteristic curve (AUC) with the DeLong test.

Study Type

OBSERVATIONAL

Enrollment

225

Conditions

Breast Cancer

Interventions

MRIDIAGNOSTIC_TEST

MRI based classification of breast cancer histological factors and subtypes

Eligibility

Sex: FEMALEMin age: 27 YearsMax age: 86 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosed with invasive breast cancer Exclusion Criteria: * Diagnosed with other cancer

Locations (1)

Bo Kyoung Seo

Ansan, South Korea

Outcomes

Primary Outcomes

The signal intensity of MRI according to histological factors and subtypes of breast cancer

Quantitative image values obtained from ultrafast MRI show similar performance in classifying histological factors and subtypes compared with standard MRI.

Time frame: Baseline, pre-surgery

Data from ClinicalTrials.gov

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