The goal of this clinical trial is to evaluate the effect of intraoperative terlipressin on the incidence of early postoperative acute kidney injury in deceased doner liver transplantation. Patients were randomly divided into experimental group and control group by numerical randomization table. The experimental group was injected with terlipressin perioperative and the control group was injected with placebo
acute kidney injury is a relatively common complication in patients with liver transplantation. Most centers have established prediction models for acute kidney injury after liver transplantation, but the incidence cannot be reduced through perioperative anesthesia management. As an vasopressin receptor agonist, terlipressin can increase blood pressure and improve kidney perfusion at the same time, and perioperative application may reduce the incidence of postoperative acute kidney injury
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
104
The medication is dispensed by the nursing staff before surgery and given to the anesthesiologist before the procedure begins
The medication is dispensed by the nursing staff before surgery and given to the anesthesiologist before the procedure begins
Beijing Tsinghua Chang Gung Hospital
Beijing, Beijing Municipality, China
RECRUITINGIncidence of acute kidney injury after liver transplantation
acute kidney injury diagnostic criteria (2012 edition)
Time frame: in 7 days
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