This is an observational study of patients diagnosed with pancreatic cancer by pathology, with a control group of patients with pathology suggestive of benign pancreatic lesions and normal subjects, and the diagnostic ability of exosomes to identify patients with pancreatic cancer was assessed through the detection of exosomes in the peripheral blood.
Study Type
OBSERVATIONAL
Enrollment
400
Xinhua Hospital, Affiliated to Shanghai Jiao Tong University, School of Medicine
Shanghai, Shanghai Municipality, China
Characterization of proteins in tumor exosomes from patients with pancreatic cancer
We will select specific protein A from circulating exosomes of pancreatic cancer patients for further analysis.
Time frame: Up to 2 years from start of study
The expression of protein A in the circulating exosomes from patients
By detecting the expression of protein A in circulating exosomes of patients. the ROC curve of A+ circulating exosomes will be compared to clinical standard tumor biomarkers (e.g., CA199) in pancreatic cancer patients.
Time frame: Up to 2 years from start of study
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