Efficacy of Lavender Essential Oil Chest Wraps in Infants With Bronchiolitis

Phase 4RecruitingNCT06108648

University Hospital, Geneva400 enrolled

Overview

The goal of this clinical trial is to learn if lavender essential oil chest wraps relieve cough in infants with bronchiolitis compared to standard care. Furthermore, the researchers will evaluate if breathing difficulties, nighttime awakening and impact on parents will be improved by the lavender oil chest wraps. Infants will be randomized to receive standard care with the addition of lavender oil chest wraps or to receive standard care alone. The study will take place in two locations in Switzerland, at the Geneva University Hospital and the Fribourg Cantonal Hospital.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

400

Conditions

Bronchiolitis

Interventions

Lavender essential oil 10%, diluted in 90% olive oil

Lavender chest wrap: Before the first application pour 10-15 ml of lavender essential oil 10% evenly on the cotton cloth. Put the soaked cotton in the plastic bag, close it and put it to heat in two heating pads (2-5 minutes) so that the oil is distributed on all the fabric. Place the cotton cloth around the patient's chest. Cover the cotton cloth with a woolen fabric that is 2 cm larger than the cotton cloth.

Eligibility

Sex: ALLMax age: 11 Months

Medical Language ↔ Plain English

Inclusion criteria: * Bronchiolitis: clinical diagnosis based on the combination of respiratory distress (tachypnea, grunting, nasal flaring, retractions, and/or need for supplementary oxygen) and fine crackles sometimes accompanied by wheezing on auscultation. * Hospitalization. * Written informed consent. Exclusion criteria: * Patients with underlying diseases that impact respiratory or heart function (congenital heart disease, congenital malformation of the lung or airway system and severe chronic lung disease). * More than 3 episodes of bronchiolitis. * Critically ill infants who have an immediate need for intensive care unit (ICU) admission. * Respiratory deterioration needing Continuous positive airway pressure (CPAP) or transfer to ICU during study enrollment. * Atopic dermatitis, eczema or other skin lesions (particularly on the chest). * Oncologic disease. * Premature infants with mild bronchopulmonary dysplasia will not be excluded.

Locations (2)

Clinique de pediatrie, HFR Fribourg - Hopital cantonal, Switzerland

Fribourg, Switzerland

RECRUITING

Children's' Hospital, University Hospital of Geneva, Switzerland

Geneva, Switzerland

RECRUITING

Outcomes

Primary Outcomes

Cough frequency

Number of coughs per hour measured with Hyfe CoughMonitor (Hyfe Inc)

Time frame: Up to 2 days

Secondary Outcomes

Crying episodes

Number of crying episodes noted by parents on crying calendar

Time frame: Up to 2 days

Respiratory rate

Number of breaths per minute

Time frame: Baseline, 1 hour, 4 hours

Oxygen supplementation requirement

Presence of oxygen supplementation during hospital stay (yes/no)