Treatment of Knee Osteoarthritis (KOA) by Injection of Autologous Adipose-derived Vascular Matrix Components (SVF) Into Joint Cavity

Inclusion Criteria: * The age range is 20-70 years old * Patients with unilateral or bilateral knee degenerative inflammation (KOA) with Kellgren-lawrence rating of level 3 or lower * The physical health status is mainly in the ASA grade Ⅰ, Ⅱ and Ⅲ * Subjects had no active tumors, no active inflammation, no treponema pallidum, HIV, hepatitis B virus, or hepatitis C virus * The subject shall provide the physical examination report of knee X-ray examination, MRI examination and other items Exclusion Criteria: * Patients with nonunion or displaced fractures around defective cartilage * Pregnant or lactating women * Autoimmune disease * Subjects with diabetes (exceptions are patients whose blood sugar levels remain within the normal range and diabetes has not caused other complications) * The patients had severe neurological diseases affecting the evaluation of postoperative results