A Correlation Study of Internal Jugular Vein Variability Under Deep Inhalation and Propofol-induced Hypotension

Affiliated Hospital of Jiaxing University64 enrolled

Overview

The correlation between internal jugular vein variability during deep inhalation and the decrease in blood pressure during propofol induction.

1. Ultrasound records at least one quiet breathing cycle and one deep inhalation cycle to calculate IJVV 2. Propofol was infused target-controlled at 4 μg/ml, and changes in arterial blood pressure within 3 minutes of propofol induction were observed. 3. Aim to conduct a prospective observational study to evaluate the correlation between internal jugular vein variability during deep inhalation and the decrease in blood pressure during propofol induction.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Hemodynamic

Eligibility

Sex: ALLMin age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age over 60 years * American Society of Anesthesiology (ASA) status Ⅱ-Ⅲ * Surgery with radial artery puncture * Propofol induction Exclusion Criteria: * BMI≥30kg/m2 * People with short necks; * Previous hypotension (systolic blood pressure \<90mmHg or mean arterial pressure \<65mmHg) * Previous poorly controlled hypertension * Cardiac insufficiency , EF value\<50% * Upper limb deep vein thrombosis * History of radiotherapy or neck surgery * Inability to maintain a supine position for necessary measurements * Mechanical ventilation status or inability to take deep breaths patients * gastrointestinal surgery * patients allergic to propofol.

Locations (1)

Affiliated Hospital of Jiaxing University

Jiaxing, Zhejiang, China

Outcomes

Primary Outcomes

IJVV during deep inhalation

IJVV (%) = (diamax - diamin)/\[(diamax + diamin)/2\] × 100

Time frame: 1 year

Data from ClinicalTrials.gov

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