This is a randomized control trial with a parallel design. Eligible patients will be randomly assigned into two groups: a control group which will be holding tube feeding when the GRV reaches 200 mL, and an experimental group will hold tube feeding when the GRV reaches 300 mL. Enteral feeding will be administered according to the study flow chart.
Background: Malnutrition is a common issue among critically ill patients. which increases hospital stays, costs, and mortality rate. According to the study, the primary reason for nurses to hold enteral nutrition is elevated gastric residual volume (GRV). However, there is still no consensus on the definition of high residual gastric volume, there is currently no consensus among experts and scholars regarding the threshold for holding enteral nutrition. Clinical nurses may prematurely hold enteral nutrition due to concerns regarding potential side effects such as vomiting and choking. The aim of this study is to increase the threshold for holding enteral feeding based on the results of the study, in order to improve nutritional intake in critically ill patients in internal medicine. Objective: Increase the nutritional intake of critically ill patients in the Department of Internal Medicine by increasing the threshold for holding tube feeding. Methods: This is a randomized control trial with a parallel design. Eligible patients will be randomly assigned into two groups: a control group which will be holding tube feeding when the GRV reaches 200 mL, and an experimental group will hold tube feeding when the GRV reaches 300 mL. Enteral feeding will be administered according to the study flow chart. The outcome data will collected based on the medical chart including frequency of diet volume ratio (diet received/diet prescribed), incidence of gastrointestinal complications, ventilator days, Ventilator-associated pneumonia, length of intensive care unit(ICU) stay, changes in nutritional indicators, APACHE Ⅱ and Duration of parenteral nutrition use. Expected result: The results of this study will provide evidence regarding the improved effectiveness and safety of increasing the threshold of GRV in medical ICU and inform future evidence-based practice.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Enrollment
230
Hold enteral feeding when GRV reaches 200 mL(current standard)
National Taiwan University Hospital
Taipei, Taiwan
Frequency of diet volume ratio
Time frame: 1 day (Transfer from the Intensive Care Unit)
Incidence of gastrointestinal complications
Abdominal distension, nausea, vomiting, diarrhea, constipation
Time frame: 1 day (Transfer from the Intensive Care Unit)
Days of ventilator use
Time frame: A week(Transfer from the Intensive Care Unit)
Ventilator-associated pneumonia
Diagnosis form clinical doctor according to chest x-ray
Time frame: 1 day (Transfer from the Intensive Care Unit)
Length of stay in the intensive care unit
Time frame: A week(Transfer from the Intensive Care Unit)
Days of parenteral nutrition use
Time frame: A week(Transfer from the Intensive Care Unit)
Acute Physiology and Chronic Health Evaluation score
an integer score from 0 to 71 is computed based on several measurements; higher scores correspond to more severe disease and a higher risk of death.
Time frame: 1 day (Transfer from the Intensive Care Unit)
Nutrition Risk Screening 2002(NRS2002)
The NRS-2002 was developed by Kondrup et al., and is meant to be a generic tool in the hospital setting-that is, useful in detecting most of the patients who would benefit from nutritional therapy. The NRS-2002 is a simple and well-validated tool that incorporates pre-screening with four questions. If one of these is answered positively, a screening follows which includes surrogate measures of nutritional status, with static and dynamic parameters and data on the severity of the disease (stress metabolism). For each parameter, a score from 0 to 3 can result. Age over 70 years is considered a risk factor and is included in the screening tool, giving 1 point. A total score of ≥3 points means that the patient is at risk of malnutrition or already malnourished.
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Time frame: 1 day (Transfer from the Intensive Care Unit)
Albumin in g/dL
Time frame: 1 day (Transfer from the Intensive Care Unit)
C-reactive protein in mg/dl
Time frame: 1 day (Transfer from the Intensive Care Unit)
Body mass index
Time frame: 1 day (Transfer from the Intensive Care Unit)