The objective is to test ex-vivo the effects of two probiotic solutions (Lactibiane ATB and Lactibiane Enfant) and five classes of drugs (antibiotic, proton pump inhibitor, non-steroidal anti-inflammatory, anxiolytic and anti-depressant) on microbial microcosms derived from human stool samples (from adults and children) re-cultured under anaerobic conditions.
Study Type
OBSERVATIONAL
Enrollment
14
1 stool sample is taken during the study with a stool sample kit
Amandine FRY
Dijon, France
Transcriptional activity of microbiomes
Transcriptional activity of microbiomes by sequencing of 16S rRNA vs. the gene encoding 16S rRNA
Time frame: 10 months
Transcriptomic profiles of the communities
Transcriptomic profiles of the communities assessed by meta-transcriptomics
Time frame: 10 months
Metabolites produced and microbial metabolic pathways
Metabolites produced and microbial metabolic pathways will be assessed by global metabolomics
Time frame: 10 months
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