The North Kynouria Project was initiated to study cardiovascular/stroke risk factors by employing mass screening and long-term surveillance of an adult population in the municipality of North Kynouria, in the county of Arcadia, Peloponnese, Greece. The North Kynouria Study was initiated to assess modifiable and non-modifiable determinants of cerebrovascular and coronary heart disease.
BACKGROUND: The North Kynouria Project is a longitudinal, interventional-behavioural, prospective study aiming to identify cardiovascular/stroke risk factors, in the adult population of the municipality of North Kynouria, in the county of Arcadia, Peloponnese, Greece. The project, initiated in November 2022, recruits volunteers, of both sexes, over 18 years of age, irrespective of their personal history of cardiovascular disease. The epidemiology and burden of cardiovascular disease in North Kynouria remain unknown. The study aims to explore and document the prevalence of major cardiovascular/stroke risk factors, as well as the nutritional status, cigarette smoking, exercise habits, alcohol consumption, and overall quality of life of the inhabitants. DESIGN NARRATIVE: The screening exam is conducted at the Astros, Health Center, by obtaining the patient's personal history, and information about the patient's habits, such as physical activity, smoking, and alcohol consumption. Body weight, height, and waist-to-hip ratio are also measured. During the examination, blood pressure is evaluated using a pre-specified protocol, including assessment of orthostatic hypertension. Further testing includes electrocardiography, ankle-brachial index, direct ophthalmoscopy, and carotid and cardiac ultrasound. Blood samples are collected and stored at the deep freeze of the Astros premises, and blood count, lipid panel, and liver and kidney function are measured. The main field of interest is the prevalence and burden of risk factors and cardiovascular disease in the wider region of North Kynouria, Arcadia Greece. The project aims to assess the epidemiology of CVD and consequently improve public health and engage with the local community through healthy behavioral education.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
PREVENTION
Masking
NONE
Enrollment
7,000
Patient counseling, lifestyle modifications, medication evaluation, and adherence
Astros Health Care Center
Ástros, Greece
RECRUITINGMajor adverse cardiovascular events
myocardial infarction, ischemic and hemorrhagic stroke
Time frame: up to 5 years after enrollment
All-cause mortality
Death by any cause, cardiovascular, infection, cancer, other
Time frame: up to 5 years after enrollment
Hospitalizations
Any cause hospitalization
Time frame: up to 5 years after enrollment
Emergency room visits
Any cause of emergency room visit
Time frame: up to 5 years after enrollment
New diagnosis of Arterial hypertension
Any diagnosis of arterial hypertension, masked, white-coat, nocturnal
Time frame: up to 1 year after enrollment
New diagnosis of diabetes mellitus
Type 1 or Type 2
Time frame: up to 1 year after enrollment
New diagnosis of dyslipidemia
New diagnosis or uncontrolled
Time frame: up to 1 year after enrollment
New diagnosis of carotid atherosclerosis
Evaluation of carotid artery stenosis
Time frame: up to 1 year after enrollment
New diagnosis of peripheral artery disease
Ankle Brachial Index evaluation
Time frame: up to 1 year after enrollment
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