Desflurane and Sevoflurane on Remifentanil Requirement

Ajou University School of Medicine78 enrolled

Overview

The primary purpose of this study is to compare the desflurane and sevoflurane on remifentanil requirement using analgesia nociception index-guided anesthesia in patients undergoing spine surgery.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

Conditions

Spinal Diseases

Interventions

Desflurane Inhalation SolutionDRUG

Keeping the anesthesia using desflurane inhalation solution as 1 minimal alveolar concentration

Sevoflurane Inhalation SolutionDRUG

Keeping the anesthesia using sevoflurane inhalation solution as 1 minimal alveolar concentration

Eligibility

Sex: ALLMin age: 19 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Clinical diagnosis of herniated disc, injury of spinal cord, and neoplasm of spinal meninges Exclusion Criteria: * Hyperbilirubinemia * Prior chronic pain * Prior opioid abuse * Cardiac arrythmia

Outcomes

Primary Outcomes

remifentanil requirement

assessing the total dose of remifentanil administered from skin incision until skin suture

Time frame: at time of the end of skin suture (up to 3 hours)

Data from ClinicalTrials.gov

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