Exercise CMR in (p)LF-LG AS

University of Göttingen100 enrolled

Overview

Patient with paradoxical or conventional low-flow low-gradient aortic stenosis on echocardiographic assessment will undergo physiological exercise-stress CMR in addition to guideline recommended surveys prior to TAVR.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Aortic Stenosis, Severe

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * paradoxical or conventional severe low-flow low-gradient aortic stenosis Exclusion Criteria: * CMR incapable device * unable to undergo 40 min scan (can not lie flat, claustrophobia) * renal insufficiency (eGFR \<30 ml/min/1.73m²) * allergy against contrast agent * unable to exercise in supine position

Locations (1)

University Hospital Goettingen

Göttingen, Germany

RECRUITING

Outcomes

Primary Outcomes

Composite of events: number of participants with cardiovascular death or heart failure hospitalisation

Time frame: 12 months

Data from ClinicalTrials.gov

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