More than 30% of people hospitalized with decompensated heart failure return to the hospital within 90 days. Emerging evidence suggests that hemodynamic monitoring with guided management may enhance prognosis and management. Hemodynamic monitoring with echocardiography using diastology and an evidence-informed therapeutic protocol have the potential to achieve this aim in a minimally invasive manner.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
30
We will follow American Society of Echocardiography criteria to determine the degree of diastolic dysfunction after performing each focused echocardiogram.
If the daily urine output or weight loss are less than study-specified targets, then the research team will recommend changes to the diuretic regimen based on the degree of diastolic dysfunction.
Clinicians will rely on usual care metrics and parameters to guide diuresis.
Recruitment Rate
This is calculated as the number of participants enrolled in the study per month.
Time frame: 12 months (anticipated study duration)
Compliance with Echocardiograms
This is calculated as the number of echocardiograms completed divided by the number scheduled as per the study protocol.
Time frame: 12 months (anticipated study duration)
Interpretability of Echocardiograms
This is calculated as the number of studies without indeterminate diastolic dysfunction divided by the total number of studies performed.
Time frame: 12 months (anticipated study duration)
Adherence to Protocol Recommendations
This is calculated as the number of treatment decisions in the intervention arm that is aligned (increase, maintain, or decrease) with the therapeutic recommendations of the trial based on the severity of diastolic dysfunction divided by the number of studies completed.
Time frame: 12 months (anticipated study duration)
Follow-Up at 30 and 90 Days
This is calculated as the number of participants that complete a follow-up visit with a study team member at 30 and 90 days, respectively.
Time frame: 12 months (anticipated study duration)
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