In-Hospital Detection of Elevated Blood Pressure

Annina Vischer800 enrolled

Overview

The goal of this clinical trial is to analyse the prevalence of new or uncontrolled arterial hypertension (AHT) after hospital discharge of medical in-patients with elevated blood pressure (BP) values during hospitalisation. The main questions it aims to answer are: * Do elevated BP values during hospitalisation correspond to new or uncontrolled AHT after hospital discharge? * Is it safe to postpone adaption of antihypertensive treatment until after proper evaluation of AHT after hospital discharge? Participants will either be treated according to their physicians' decision or antihypertensive treatment adaptions will be postponed until after hospital discharge.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

SINGLE

Enrollment

800

Conditions

Hypertension Blood Pressure, High

Interventions

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patient hospitalized on the internal medicine ward for non-cardiovascular causes, i.e. patients hospitalized for conditions, which are not acutely worsened by uncontrolled AHT * Asymptomatic elevated BP values (defined as 140-180 mmHg systolic and/or 90-110 mmHg diastolic) on at least 2 occasions * Ability to understand study procedures and to provide written informed consent Exclusion Criteria: * Hospitalization for any conditions which can be worsened by uncontrolled AHT: * Cerebrovascular events * Acute coronary syndrome * Acute or decompensated heart failure * Any condition preventing ABPM * Pregnant or lactating women * Failure to provide informed consent

Outcomes

Primary Outcomes

Prevalence of persisting new or uncontrolled arterial hypertension

Elevated blood pressure values in ambulatory blood pressure monitoring

Time frame: 4 weeks after hospital discharge

Prevalence of a combined hypertensive complication endpoint

Consisting of intracerebral bleeding, ischemic stroke, myocardial infarction, cardiovascular death or cardiovascular re-hospitalization

Time frame: Until 4 weeks after hospital discharge

Prevalence of a combined hypotensive complication endpoint

Consisting of falls, acute kidney injury, electrolyte disturbances, re-hospitalizations due to hypotension, or BP values on ABPM below the lower treatment limit

Time frame: Until 4 weeks after hospital discharge

Secondary Outcomes

Clinic blood pressure measurement in mmHg

Documented in the patient documentation

Time frame: At baseline

Research blood pressure measurement in mmHg

Standardized blood pressure measurement taken by research staff

Time frame: At baseline

Prevalence of previously unknown arterial hypertension

No previously documented diagnosis of arterial hypertension and no antihypertensive treatment

Time frame: At baseline

Prevalence of female gender

As reported by participant

Time frame: At baseline

Prevalence of re-hospitalization for any cause

According to hospital documentation and patient interrogation

Time frame: Until 4 weeks after hospital discharge

In-Hospital Detection of Elevated Blood Pressure

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Secondary Outcomes

Central Contacts