A Multi-omics-based Metabolic Typing Study of Gastric Cancer

Zhejiang Cancer Hospital480 enrolled

Overview

In the study, the investigators obtained gastric cancer tissues from 480 gastric cancer patients who had undergone surgery at the Zhejiang Cancer Hospital's biospecimen bank between 2012-2019, and obtained relevant clinical information. The gastric cancer tissues were subjected to transcriptomic, metabolomic and other multi-omics testing, and analyzed for the metabolic changes of gastric cancer, and proposed to discover relevant therapeutic targets.

Study Type

OBSERVATIONAL

Enrollment

480

Conditions

Gastric Cancer Multi-omics Diagnosis

Interventions

Without any interventionOTHER

There were no special interventions for the two groups.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 18≤age≤80 * Histologically or cytologically confirmed gastric cancer * Undergo surgery for radical or palliative gastric cancer (both open and laparoscopic) * Patients with survival follow-up information Exclusion Criteria: * Two or more kinds of malignant tumors at the same time * Incomplete or missing case information * Preoperative diagnosis of residual gastric cancer

Locations (1)

Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Hangzhou, Zhejiang, China

Outcomes

Primary Outcomes

The differences of the metabolism information

The differences of the metabolism information between gastric cancer tissues and non-cancerous gastric cancer tissues. These data included Metabolizing enzyme mRNA expression and metabolite content.

Time frame: through study completion, an average of 6 months

Data from ClinicalTrials.gov

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