Nasopharyngeal carcinoma (NPC) is a type of head and neck cancer. The last three decades of research in head and neck radiation oncology have largely focused on improvements in survival, which have mostly come at the cost of long term toxicity for surviving patients.This is an observational study that is being done to evaluate the long-term efficacy, learn about the toxicity and quality of life that survivors of nasopharyngeal carcinoma may have following treated with reduced volume intensity modulated radiation therapy.
Study Type
OBSERVATIONAL
Enrollment
500
Department of radiation oncology, Fujian cancer hospital
Fuzhou, Fujian, China
Overall survival
Overall survival is calculated from diagnosis to death from any cause
Time frame: 10 years
Loco-regional failure-free survival
Loco-regional failure-free survival is calculated from diagnosis to the first loco-regional failure
Time frame: 10 years
Failure-free survival
Failure-free survival rate is calculated from the date of diagnosis to the date of treatment failure or death from any cause, whichever is first
Time frame: 10 years
Distant failure-free survival
Distant failure-free survival is calculated from diagnosis to the first remote failure
Time frame: 10 years
Quality of Life Questionnaires QLQ-C30
Quality of life as measured by QLQ-C30
Time frame: 1year
Quality of Life Questionnaires
Quality of life as measured by QLQ H\&N35
Time frame: 1year
Evaluation of late toxicities
Clinical toxicities will be grade according to RTOG/CTCAE
Time frame: 1year
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