The goal of this clinical trial is to determine if adding avocados to the diet of impacts cognition in 70 older adults, age 65-85, without dementia. We will test for change in functional MRI, cognitive performance, and brain blood flow. Intervention group participants will be asked to consume 1 avocado per day for 12 weeks. Participants in the control group will be asked to continue their normal intake for 12 weeks. Throughout the study, participants will be asked to perform cognitive tests, MRI, blood tests, and questionnaires.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
70
Participants will consume provided avocados daily and track consumption for the duration of the study. Participants will be adding avocados to their diet and will receive education on maintaining usual diet.
University of Kansas Medical Center
Kansas City, Kansas, United States
RECRUITINGChange in brain activity
MRI will be used to measure changes in brain activity during resting state, a working memory task, and executive function task.
Time frame: Baseline and 12 weeks
Changes in cerebral blood flow
MRI will be used to measure change in cerebral blood flow.
Time frame: Baseline and 12 weeks
Changes in memory and executive function
NIH Toolbox will be used to measure change in cognition throughout the study.
Time frame: Baseline and 12 weeks
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