The goal of this quasi-experimental study is to test effect of time-restricted eating on cognitive function and other biopsychosocial factors in menopausal women undertaking a 12-week exercise programme. The main questions to answer are: 1. What is effect of time-restricted eating on cognitive function in menopausal women undertaking a 12-week exercise programme? 2. What is effect of time-restricted eating on menopausal symptoms in menopausal women undertaking a 12-weeks exercise programme? 3. What is effect of time-restricted eating on metabolic health parameters in menopausal women undertaking a 12-weeks exercise programme? Participants of both groups will have moderate intensity circuit mixed endurance and resistance exercise programme two times per week for 55 minutes for 12 weeks. Participants of one of two groups will not only exercise but also have a time-restricted eating following 16:8 protocol for 12 weeks. Participants will have pre-tests and post-tests: * blood samples collection (to measure level of brain-derived neurotrophic factor, glial cell derived neurotrophic factor, insulin, glucose, lipid profile), * body composition analysis, * Stroop test and N-back test, * electroencephalography using Emotiv Epic X devices, * One-repetition maximum test, Ruffier test, * Questionnaire assessment (using Menopause Rating Scale and The Menopause-Specific Quality of Life Questionnaire). Researchers will compare two groups - exercise group and combination group which will do both time-restricted eating and exercise to see if there is a modulating effect of time-restricted eating in participants undertaking exercise.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
80
Moderate intensity circuit mixed endurance and resistance exercise programme two times per week for 55 minutes for 12 weeks and a time-restricted eating following 16:8 protocol for 12 weeks.
Moderate intensity circuit mixed endurance and resistance exercise programme two times per week for 55 minutes for 12 weeks only.
Poznan University of Physical Education
Poznan, Greater Poland Voivodeship, Poland
Brain-derived neurotrophic factor
Level of brain-derived neurotrophic factor in ng/ml
Time frame: Before and after 12-week intervention
Glial cell derived neurotrophic factor
Level of glial cell derived neurotrophic factor in ng/ml
Time frame: Before and after 12-week intervention
Insulin
Level of insulin in μIU/ml
Time frame: Before and after 12-week intervention
Glucose
Level of glucose in mg/dl
Time frame: Before and after 12-week intervention
LDL-cholesterol
Level of cholesterol LDL in mg/dl
Time frame: Before and after 12-week intervention
Muscle mass
Bioelectrical impedance analysis for estimating body composition, in particular muscle mass in kg
Time frame: Before and after 12-week intervention
Fat mass
Bioelectrical impedance analysis for estimating body composition, in particular fat mass in kg
Time frame: Before and after 12-week intervention
Stroop test
Cognitive functions assessment with Stroop test in points. Higher scores means better outcome.
Time frame: Before and after 12-week intervention
N-back test
Cognitive functions assessment with N-back test in points. Higher scores means better outcome.
Time frame: Before and after 12-week intervention
Electroencephalography
Measurement of brain waves (alpha, beta, gamma, theta) to assess electrical activity of the brain using Emotiv Epoc X device
Time frame: Before and after 12-week intervention
One-repetition maximum test
Strength assessment with one-repetition maximum test in kg
Time frame: Before and after 12-week intervention
Ruffier test
Cardiorespiratory fitness assessment with Ruffier test in points. Minimum value is 0, maximum value is 10. Higher score means worse outcome.
Time frame: Before and after 12-week intervention
Menopause Rating Scale
Menopausal symptoms assessment with Menopause Rating Scale in points. Minimum value is 0 and maximum value is 44. Higher score means worse outcome.
Time frame: Before and after 12-week intervention
The Menopause-Specific Quality of Life Questionnaire
Menopausal symptoms assessment with The Menopause-Specific Quality of Life Questionnaire in points. Minimum value is 0 and maximum value is 174. Higher score means worse outcome.
Time frame: Before and after 12-week intervention
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