Effects of Dexmetomidine and Remifentanil Used for Controlled Hypotension in Septorhinoplasty Surgery on Cardiac Electrophysiology: Prospective Randomized Study

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital72 enrolled

Overview

Our aim in this treatment was to reveal the effects of remifentanil and dexmetomidine, which we used to provide controlled hypotension in septorhinoplasty surgery, on cardiac electrophysiology. We planned to compare the patients by recording preoperative and postoperative ECGs. We also planned to record the patients' intraoperative blood pressure, saturation, and pulse rate, rickeragitation scale, and vas score.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Rhinoplasty Surgery

Interventions

DexmedetomidineDRUG

Eligibility

Sex: ALLMin age: 17 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * patients with an ASA score of I and between the ages of 17-45 years, who were to undergo general anesthesia with sevofulurane were included in the study. Exclusion Criteria: Patients aged \<17 and \>45 years, patients with liver and/or kidney failure, obese patients (BMI \>30), trauma patients, ASA II-III-IV patients, patients with bleeding disorders, those using drugs that may affect the coagulation system, patients with cardiomyopathy, cerebrovascular disease, immobility, and malnutrition were excluded from the study. \-

Outcomes

Primary Outcomes

iceb

Qt\\Qrs

Time frame: preoperative and postoperative (immediatly after extubation)

Secondary Outcomes

Riker Agitation Scale

7 -Dangerous Agitation, 6 - Very Agitated, 5 - Agitated, 4 - Calm and Cooperative, 3 - sedated, 2- Very Sedated, 1 -Unarousable

Time frame: Immediately after extubation

mean arterial pressure

mmHg

Time frame: when you come to the operating room table after anesthesia induction Intraoperative 30 minutes after extubasion

heart rate

beats\\minute

Time frame: when you come to the operating room table after anesthesia induction Intraoperative 30 minutes after extubasion

Numeric Rating Scale

They will be numbered from 1 to 10. 1 mildest 10 most severe pain

Time frame: Postoperative 0-2 hours