Aim: to determine to what extent meal composition influences postprandial sensations. Experimental design: randomized cross-ower study comparing the responses to a high protein (47.3% protein, 39.4% carbohydrates, 13.3% lipids) versus a balanced (22.2% protein, 67.85% carbohydrates, 9.95% lipids). In each participant the meals (both containing 20.8 g protein and diluted to a volume of 200 mL) will be tested on separate days. Healthy, non-obese participants (8 men and 8 women) will be instructed to eat a standard dinner the day before, to consume a standard breakfast at home after overnight fast, and to report to the laboratory, where the test meal will be administered 3 h after breakfast. Studies will be conducted in a quiet, isolated room with participants sitting on a chair. Perception will be measured at 5 min intervals 10 min before and 20 min after ingestion, at 10 min intervals up to 60 min after the meal and at 30 min up to 120 min after ingestion. Blood samples for biochemical and hormonal determinations will be taken before and after ingestion.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Enrollment
16
High protein supplement 200 mL
Balanced supplement 200 mL
University Hospital Vall d'Hebron
Barcelona, Spain
Change in digestive well-being measured after the test meal
Change in average well-being measured by 10 score scales at the end of the test meal.
Time frame: 1 day
Change in satiety measured after the test meal
Change in average satiety measured by 10 score scales at the end of the test meal
Time frame: 1 day
Change in fullness sensation measured after the test meal
Change in average fullness measured by 10 score scales at the end of the test meal
Time frame: 1 day
Change in abdominal discomfort/pain sensation measured after the test meal
Change in average abdominal discomfort/pain measured by 10 score scales at the end of the test meal
Time frame: 1 day
Change in mood measured after the test meal
Change in average mood measured by 10 score scales at the end of the test meal.
Time frame: 1 day
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