Real-world disease outcomes and safety in patients with mild to moderate COVID-19 treated with JT001
Study Type
OBSERVATIONAL
Enrollment
7,656
oral administration
Peking university first hospital
Beijing, Beijing Municipality, China
Shanghai Fourth People's Hospital
Shanghai, Shanghai Municipality, China
Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Shanghai, Shanghai Municipality, China
Gongli Hospital, Pudong New Area, Shanghai
Shanghai, Shanghai Municipality, China
Incidence of COVID-19 disease progression (severe COVID-19 or all-cause death) by day 28
Incidence of COVID-19 disease progression (severe COVID-19 or death from any cause) at day 28 from COVID-19 diagnosis. According to the diagnosis of severe COVID-19 and indicators meeting the diagnostic definition of severe COVID-19, the evaluation and analysis were performed.
Time frame: Within 28 days
Incidence of the following COVID-19 disease progression events by day 28
Severe COVID-19 or all-cause death in patients with high-risk factors,Elderly patients (≥65 years) with severe COVID-19 or all-cause death,All enrolled patients had severe COVID-19,All enrolled patients died from all causes,COVID-19 related hospitalizations in non-hospitalized patients,Hospitalized patients with severe COVID-19 or all-cause death.
Time frame: Within 28 days
Incidence of severe Covid-19-related events up to day 28
Incidence of severe Covid-19-related events up to day 28,Respiratory rate ≥30 times/min, Oxygen saturation (SpO2) ≤93% ,Partial oxygen pressure (PaO2)/Oxygen concentration (FiO2) ≤300mmHg,Lung imaging showed significant lesion progression \> 50% within 24 to 48 hours,Mechanical ventilation o Respiratory failure and mechanical ventilation,Shock,Stay in ICU,Organ failure and admission to ICU.
Time frame: Within 28 days
The incidence of all aes and abnormal laboratory changes on day 28, etc
The incidence of all aes and abnormal laboratory changes on day 28, etc
Time frame: Within 28 days
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Central Hospital of Minhang District, Shanghai
Shanghai, Shanghai Municipality, China
Shanghai Pudong Hospital, Fudan University Affiliated Pudong Medical Center
Shanghai, Shanghai Municipality, China