Polycystic ovary syndrome (PCOS) is an endocrine disorder that affects approximately 10-20% of women of reproductive age, Management strategies for PCOS include lifestyle modifications such as diet and physical activity that are the first-line approach to treatment; however, they are reported to be minimally effective in reducing weight or treating PCOS-related symptoms.Pharmacological options are also available; however, they are not explicitly approved for PCOS treatment as they have been primarily used to treat other conditions such as T2DM
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
60
Metformin Hydrochloride 850 mg oral tablet
Vildagliptin 50 MG oral tablets
October 6 university hospital
Giza, Egypt
RECRUITINGConcentration of luteinizing hormone (LH)
serum luteinizing hormone (LH)
Time frame: at baseline and after 3 months
Concentration of Follicle-stimulating hormone
Serum Follicle-stimulating hormone
Time frame: at baseline and after 3 months
Concentration of Free androgen index
serum Free androgen index
Time frame: at baseline and after 3 months
Concentration of total testosterone
serum total testosterone
Time frame: at baseline and after 3 months
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