To investigate the efficacy of vestibular rehabilitation treatment on unsteadiness after intratympanic gentamicin in patients with Meniere's disease.
Previous studies have generally focused on the efficacy of VRT for Meniere's disease, with little attention paid to the effect of VRT on MD patients who still have vestibular dysfunction even after intratympanic gentamicin treatment. The aim of this study is to compare the efficacy of VRT with usual care in MD patients who experience persistence of unsteadiness 1 month after intratympanic gentamicin treatment, in order to understand whether VR has a positive impact on balance maintenance and vertigo control in MD patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
48
Include anti-dizziness medications, diuretics, or hormone therapy.
Include comprehensive health education, fall prevention and lifestyle adjustments.
Encompass office-based sessions of vestibular rehabilitation treatment once weekly, supplemented by home-based exercises conducted two or three times daily for the remaining duration of the study.
Otorhinolaryngology Department of Affiliated Eye and ENT Hospital, Fudan University
Shanghai, Shanghai Municipality, China
Functional Gait Assessment (FGA)
FGA is a semi-quantitative measure of walking balance ability.
Time frame: Change from baseline, at 8 weeks and 6 months post-randomization
Sensory Organization Test (SOT)
SOT is a form of posturography, aiming to distinguish and assess the weight of vestibular, visual, and proprioceptive sensations in maintaining balance.
Time frame: Change from baseline, at 8 weeks and 6 months post-randomization
Meniere's Disease Outcomes Questionnaire (MDOQ)
MDOQ is a comprehensive assessment of MD patients' quality of life (QOL) in three dimensions: physical, emotional, and social.
Time frame: Change from baseline, at 8 weeks and 6 months post-randomization
Visual Vertigo Analogue Scale (VVAS)
In VVAS, patients estimate the intensity of their symptoms related to dizziness, vertigo, and imbalance.
Time frame: Change from baseline, at 8 weeks and 6 months post-randomization
Vestibular Activities and Participation Measure (VAP)
VAP is a 34-item self-report questionnaire, aiming to evaluate the extent of activity limitations and participation restrictions created by vestibular disorders.
Time frame: Change from baseline, at 8 weeks and 6 months post-randomization
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