The primary endpoint of this study is the completion time of hemostasis treatment when administered Fresh frozen plasma (FFP) and frozen powder coagulation factor concentrate (PCC) in goal-directed bleeding management for non-cardiac surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
154
transfusion of fresh frozen plasma
prothrombin complex concentrate administration
duration from the time diagnosing r-time prolongation to the time achieving bleeding control
Time frame: 1 min
Red Blood Cell amount
Red Blood Cell transfusion amount during surgery
Time frame: 1 hour
FFP amount
FFP transfusion amount during surgery
Time frame: 1 hour
Platelet amount
Platelet transfusion amount during surgery
Time frame: 1 hour
r-time
CK r-time after PCC or FFP
Time frame: 10 min
CRT-MA
CRT-MA after PCC or FFP
Time frame: 10 min
CFF-MA
CFF-MA after PCC or FFP
Time frame: 10 min
Bleeding
Postoperative bleeding amount
Time frame: 6 hour
oxygenation profile
PaO2/FiO2 ratio
Time frame: 1 hour
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