Different Dietary Patterns

University of Vienna16 enrolled

Overview

The aim of the present study is to determine the effects of different standardized dietary patterns on general health markers, intestinal function, immune response and affective processes/ cognitive skills in healthy subjects.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Diet, Healthy Endotoxemia

Interventions

Dietary interventionOTHER

Participants receive diets following different dietary patterns for 1 week.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * BMI between 18.5 kg/m² und 24.9 kg/m² Exclusion Criteria: * Chronic inflammatory diseases * Metabolic diseases * Viral or bacterial infections in the last 3 weeks * Allergic reactions in the last 3 weeks * Intake of anti-inflammatory drugs * Malignant diseases * Pregnancy and lactation * Smoking * Alcohol consumption \> 10 g/d for women and \> 20 g/d for men * Drug consumption * Vegetarian or vegan diet * Food intolerances

Locations (1)

University of Vienna

Vienna, Austria

RECRUITING

Outcomes

Primary Outcomes

Changes in parameters of intestinal barrier function

Changes in TLR ligand serum levels

Time frame: 1 week

Secondary Outcomes

Changes in parameters of immune response

Changes in concentration of Interleukin-6 in cell culture supernatant of stimulated immune cells

Time frame: 1 week

Changes in blood lipid levels

Changes in triglyceride, cholesterol levels \[mg/dl\]

Time frame: 1 week

Changes in cognitive skills

Assessment of cognitive processes using computer-based psychological tasks (Stroop effect; calculation of differences in response times to incongruent vs. congruent word-color associations)

Time frame: 1 week

Data from ClinicalTrials.gov

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