Memory in Neurology project (PAMNEU) aims to map the distribution and severity of cognitive impairment in patients of outpatient neurologic offices across the geographical area of the Czech Republic. 1000 patients in 50 neurologic offices will undergo cognitive tests (ALBA and PICNIR) and psychometric scales (FAQ-CZ and GDS-CZ) to asses their functional state and depressive symptoms. The trial's primary goal is to assess the distribution of cognitive impairment among diagnostic groups in neurologic care according to the ICD-10. Additionally, the feasibility of ALBA and PICNIR methods to uncover previously undiagnosed cognitive impairments will be evaluated.
Study Type
OBSERVATIONAL
Enrollment
600
Teaching Hospital Královské Vinohrady
Prague, Prague, Czechia
Baseline ALBA
Amnesia Light and Brief Assessment (ALBA) test is an innovative method to assess cognitive functions quickly. The cognitive performance is scaled as an overall score between 0-12 (a lower value denotes a more severe cognitive impairment).
Time frame: Established on Day 0 as a single assessment.
Baseline PICNIR
Picture Naming and Immediate Recall test (PICNIR) is an innovative test method to assess cognitive functions quickly. The cognitive performance is scaled as an overall score between 0-20 (a lower value denotes a more severe cognitive impairment).
Time frame: Established on Day 0 as a single assessment.
Statistical analysis of ALBA results
Statistical analysis of ALBA results compared to groups determined by ICD-10 diagnosis and demographical data.
Time frame: The final statistical analysis will be performed through study completion, an average of 6 months.
Statistical analysis of PICNIR results
Statistical analysis of PICNIR results compared to groups determined by ICD-10 diagnosis and demographical data.
Time frame: The final statistical analysis will be performed through study completion, an average of 6 months.
Baseline FAQ-CZ
Functional Activities Questionnaire - Czech version (FAQ-CZ) is a standardized questionnaire administered to assess a patient´s functional state regarding daily activities. Ten items of daily functioning are scaled between 0-3 (a higher value denotes a higher dependency) to reach the overall score between 0-30 (a higher value denotes a higher dependency). This version of the scale will be used for participants´ self-evaluation.
Time frame: Established as a baseline on Day 0.
Baseline GDS-CZ
The Geriatric Depression Scale - Czech version (GDS-CZ) is a standardized questionnaire administered to assess depressive symptoms, particularly in the elderly population. Fifteen items are scaled between 0-1 to reach the overall score between 0-15 (a higher value denotes a higher level of depressive symptoms).
Time frame: Established as a baseline on Day 0.
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