The goal of this prospective study is to learn about the operative outcomes in patients with pituitary adenoma who receive endoscopic resection. The main question it aims to answer is: • What are the outcomes of patient following endoscopic resection? including visual, hormonal, survival, and functional outcomes. Participants' data including clinical history, laboratory data, radiographic images, intraoperative videos will be evaluated and analyzed.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
500
Endoscopic endonasal transsphenoidal approach for resection of pituitary adenomas
National Cheng-Kung University Hospital
Tainan, Taiwan
RECRUITINGVisual field
The postoperative visual field will be assessed with standard visual perimetry and compared with preoperative measurements.
Time frame: 6 months
Diabetes insipidus
Postoperatively, the patient's urine output and urine specific gravity will be measured to determine if the patient had diabetes insipidus. If the patient had diabetes insipidus, the duration of the diabetes insipidus will be recorded.
Time frame: 6 months
Cortisol level
Postoperative serum cortisol level will be measured and compared to preoperative levels.
Time frame: 6 months
Thyroid hormone level
Postoperative serum TSH and free T4 level will be measured and compared to preoperative levels.
Time frame: 6 months
Prolactin level
Postoperative serum prolactin level will be measured and compared to preoperative levels.
Time frame: 6 months
IGF-1 level
Postoperative serum IGF-1 level will be measured and compared to preoperative levels.
Time frame: 6 months
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