Pre-exposure Prophylaxis (PrEP) Adherence Intervention for Women with Substance Use Disorders

Inclusion Criteria: * Black/African American and Hispanic/Latina cisgender women * diagnosed with a Substance use disorder (SUD) per Diagnostic and Statistical Manual of Mental Illnesses (DSM)-5 criteria * HIV negative * sexually active with an opposite sex partner within the past 6 months * not using PrEP for HIV prevention at the time of screening * able to speak, read, and write in English; and * own or have regular access to a smart phone. Exclusion Criteria: * be concurrently participating in another SUD behavioral treatment program * unable to provide informed consent for participation (e.g., have severe cognitive impairment that would interfere with their ability to consent, understand study procedures and/or effectively participate in therapy * have psychological distress that would prohibit them from participating in the study * be unable or unwilling to meet study requirements * be ineligible for PrEP based on Centers for Disease Control and Prevention (CDC)-defined criteria for PrEP based on substance use and sexual risk * have medical contraindications for PrEP (e.g., known renal impairment which can be exacerbated by PrEP use).