Retrospective and prospective study on patients suffering from nephrolithiasis who undergo minimally invasive surgery of the upper excretory system; correlation between the phenotypic and genotypic aspects of the patients and the stone pathology treated with an endoscopic surgical approach.
Clinical data will be collected from patients suffering from kidney stones before and after surgery, in order to demonstrate how the endoscopic approach can not only be effective in treating kidney stones but also reduce operative complications. These data will be collected in a database in order to be able to perform statistical analyzes useful for demonstrating our theory. Furthermore, data from the surgery will be collected regarding the endoscopic instruments used and the intraoperative findings (site, size, appearance of the stone), degree of calcification of the renal papillae. All this in order to improve the therapeutic approach to patients suffering from stones and reduce the risk of recurrence over time through the identification of genetic expression patterns that predispose to the expression of the stone phenotype.
Study Type
OBSERVATIONAL
Enrollment
15,000
Clinical data will therefore be acquired through a collection of medical history, physical examination, blood chemistry and instrumental test reports;
IRCCS Ospedale San Raffaele
Milan, Lombardy, Italy
RECRUITINGClinical data
Medical history: patient's medical history, past surgical history, family medical history, social history, allergies, and medications; physical examination: vital signs, temperature examination, blood pressure, pulse, and respiratory rate blood chemistry and instrumental test reports: Serum PSA levels, conventional imaging
Time frame: Baseline and after 6 months
Eating habits
Eating habits through an ad-hoc eating habits questionnaire
Time frame: Baseline and after 6 months
Prostatic Function
Prostatic Function through the International Prostatic Symptoms Score questionnaire, IPSS, Scoring 0 -7, 0-7 mild symptoms, 8-19 moderate symptoms, 20-35 severe symptoms.
Time frame: Baseline and after 6 months
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.