Effect of Prilocaine vs Bupivacaine on Hemodynamics in Spinal Anesthesia for Geriatric Patients

Cairo University112 enrolled

Overview

Data comparing prilocaine vs bupivacaine in equipotent doses in the elderly are lacking; therefore, the study will compare the effect of prilocaine vs bupivacaine on hemodynamics in spinal anesthesia for geriatric patients undergoing endoscopic urological surgeries

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

112

Conditions

Hemodynamic Instability

Interventions

PrilocaineDRUG

The patients will receive a single injection of spinal anesthesia using prilocaine plus fentanyl

BupivacaineDRUG

The patients will receive a single injection of spinal anesthesia using Bupivacaine plus fentanyl

Eligibility

Sex: ALLMin age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients aged 65 years old and above. * Both genders. * Patients scheduled to undergo endoscopic urological surgeries. * ASA I and II class. Exclusion Criteria: * Patient refusal. * Known local anesthetic (LA) allergy. * Bleeding disorders. * Skin lesions or infections at site of needle insertion. * Hypertensive patients. * Patients candidate for transurethral resection of the prostate * ASA III and VI class

Locations (1)

Kasr Alaini hospital

Cairo, Egypt

Outcomes

Primary Outcomes

Hypotension

Incidence of hypotension from local anesthetic injection

Time frame: Till 30 minutes after spinal anesthesia.

Secondary Outcomes

Use of vasopressor drugs

Total doses of vasopressor drugs used for hypotension treatment

Time frame: Until the patient will have no lower limbs motor weakness assessed up to 6 hours after spinal anesthesia

Data from ClinicalTrials.gov

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