Study on Hyperlipidemia Combined With Carotid Atherosclerosis With ShenJu Granules

Guangdong Provincial Hospital of Traditional Chinese Medicine80 enrolled

Overview

This study focuses on PWV as the main outcome, aiming to evaluate the efficacy and safety of ShenJu in treating patients with hyperlipidemia combined with carotid atherosclerosis, and provide a basis for traditional Chinese medicine treatment of hyperlipidemia combined with carotid atherosclerosis.

Hyperlipidemia is very harmful and easy to cause atherosclerosis. Atherosclerosis is the main factor of carotid atherosclerosis. Carotid atherosclerosis and plaque are usually the characteristic manifestations of atherosclerosis. Carotid arteriosclerosis is closely related to stroke, and carotid arteriosclerosis, rupture and detachment of carotid plaques, carotid stenosis and occlusion can all lead to the occurrence of cerebrovascular events. Early detection and evaluation of hyperlipidemia with carotid atherosclerosis by various means can effectively reduce the risk of cardiovascular and cerebrovascular diseases. In order to better serve the vast number of patients, Professor Wang Lei has developed ShenJu granules based on traditional Chinese medicine prescriptions and years of clinical experience. Compared to decoction, ShenJu granules have a higher concentration, are more convenient to carry, and are easy to absorb. They have received unanimous praise from patients in clinical applications.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Hyperlipidemia Carotid Atherosclerosis

Interventions

ShenJuOTHER

One package per time, twice a day, 90 days of treatment

PlaceboOTHER

One package per time, twice a day, 90 days of treatment (the placebo was basically the same as ShenJu in terms of appearance, shape, color, taste, etc.)

Eligibility

Sex: ALLMin age: 15 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. The patient has informed consent and signed the informed consent form 2. Age between 18-65 years old 3. Meet the diagnostic criteria for hyperlipidemia and accompanied by carotid arteriosclerosis 4. Meet the diagnostic criteria of TCM wet certificate: refer to the scoring standard of TCM Wet Disease Scale Exclusion Criteria: 1. Severe liver, kidney and cardiac insufficiency 2. Any other serious disease or condition such as: malignant tumor, uncontrolled severe hypertension, diabetic ketoacidosis (acute complication/vascular abnormality), arrhythmia, coagulation abnormalities 3. Have participated in another clinical study within 30 days prior to enrollment or have received a history of randomized ketoacidosis in this study 4. Pregnant women, women preparing to become pregnant and lactating women 5. Patients who are allergic to relevant Chinese medicine ingredients 6. Patients who have had a stent inserted 7. Patients who the investigator determines are not suitable to participate in this study

Locations (2)

Guangdong Provincial Hospital of Chinese Medicine

Guangzhou, Guangdong, China

RECRUITING

WangLei

Guangzhou, Guangdong, China

RECRUITING