The aim of the current study is to compare the effect of ventilator trigger sensitivity adjustment versus threshold inspiratory muscle training on arterial blood gases in mechanically ventilated patients.
Failed extubations are not uncommon in most ICUs, the failure rate ranging from 2 to 20%. Since failed extubation is associated with greater hospital morbidity and mortality and longer length of stay, it is imperative to identify screening techniques that minimize the number of failed extubations. Many studies have been done on the effect of IMT by threshold IMT and adjustment of mechanical ventilator trigger separately, thereby, it is rational to compare between two methods of training to know which is more effective to help in weaning process through its effect on ABGs.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
45
New techniques to train inspiratory muscles in mechanically ventilated patients
Kasr Al Ainy School of Medicine
Cairo, Egypt
RECRUITINGPH
To measure PH
Time frame: Pre intervention and immediate post intervention, through study completion, an average of two weeks
PaO2
To measure partial pressure of oxygen
Time frame: Pre intervention and immediate post intervention, through study completion, an average of two weeks
PaCO2
To measure partial pressure of carbon dioxide
Time frame: Pre intervention and immediate post intervention, through study completion, an average of two weeks
HCO3
To measure bicarbonate
Time frame: Pre intervention and immediate post intervention, through study completion, an average of two weeks
Rapid shallow breathing index
To measure respiratory endurance
Time frame: Pre intervention and immediate post intervention, through study completion, an average of two weeks
The Horowitz index
To measure PaO2 /FiO2 ratio
Time frame: Pre intervention and immediate post intervention, through study completion, an average of two weeks
Glasgow coma scale
To measure level of consciousness
Time frame: Pre intervention and immediate post intervention, through study completion, an average of two weeks
Riker Sedation-Agitation Scale
Arousal/sedation assessment
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Time frame: Pre intervention and immediate post intervention, through study completion, an average of two weeks
Respiratory rate
Number of breath cycles per minute
Time frame: Pre intervention and immediate post intervention, through study completion, an average of two weeks
Minute ventilation
The amount of air that enters the lungs per minute.
Time frame: Pre intervention and immediate post intervention, through study completion, an average of two weeks
Weaning success rate
Number of patients weaning from MV
Time frame: post intervention at the end of the study, an average of two weeks