Metoclopramide for Gastric Visualization in Active Upper GI Bleeding

The mean difference in EVS

total of four locations and at each location including fundus, corpus, antrum and duodenal bulb

Time frame: Through study completion, estimate 2 years

Duration of esophagogastroduodenoscopy

Time frame: 10minutes to 2 hours

Immediate hemostasis

Rate of succession of hemostasis (bleeding stop) at first EGD

Time frame: Through study completion, estimate 2 years

The need for a second look EGD within 72 hours after initial endoscopy

Rate of need for a second look EGD within 72 hours after initial endoscopy The 72-hour recurrent GI bleeding was documented and re-EGD was performed to confirm rebleeding if the following conditions were met: I) hematemesis or bloody nasogastric tube (NG) \> 6 hours after endoscopy; II) melena after normalization of stool color; III) hematochezia after normalization of stool color or melena; IV) development of tachycardia (HR ≥ 110 bpm) or hypotension(SBP ≤ 90 mmHg) after ≥ 1 hour of vital sign stability without other cause; V) hemoglobin drop of ≥ 2 g/dL after two consecutive stable hemoglobin values ( \< 0.5 g/dL decrease) ≥ 3 hours apart; VI) tachycardia or hypotension that does not resolve within 8 hours after index endoscopy despite appropriate resuscitation (in the absence of an alternative explanation), associated with persistent melena or hematochezia or; VII) persistently dropping hemoglobin of \> 3 g/dL in 24 hours associated with persistent melena or hematochezia.

Time frame: Up to 72 hours

Number of unit of red blood cell transfusion during first 24 hours

Number of of unit of red blood cell transfusions during first 24 hours

Time frame: Up to 24 hours

Length of hospital stays

Length of hospital stays of participants

Time frame: 1day - 30days

30-day rebleeding rate

rate of 30-day rebleeding of upper GI tract

Time frame: Up to 30 days