This study will unpack the behavioral intervention for migraine and determine the optimum combinations. In addition, the study will test preference and self-selection effects during the trial.
After a 4-week screening period, eligible candidates (14 headache days in 4 week period, with 8 days being migraine) will be randomized into 2 arms - * Choice Arm: allowed to choose from a menu of migraine behavioral treatment options * Random: randomized to migraine behavioral treatment options. After 6 weeks, all participants will be assessed for their migraine frequency. Patients will be considered Responders if the migraine frequency is reduced to 50%. The Non-responders (NR) of the Choice Arm will be again given a chance to pick any of the 3 arms. The NR of the randomized arm will be randomized to any of the 3 arms. The responders will continue for 6 more weeks in their original arms. By the end of the 12 weeks, all participants will complete the study, and migraine frequency will be compared between the different groups. All behavioral interventions will be delivered virtually.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
24
Migraine Behavioral Treatment involving daily activities
Stanford University
Stanford, California, United States
RECRUITINGFeasibility in terms of recruitment and adherence rates
recruitment rate, adherence rate
Time frame: 12 weeks
Migraine Frequency
migraine day frequency
Time frame: at baseline 4 weeks before randomization, week 2-6 after date of randomization, week 8-12 after date of randomization
Headache Self-efficacy
headache self-efficacy measured using validated headache self-efficacy questionnaire
Time frame: at baseline 4 weeks before randomization, week 2-6 after date of randomization, week 8-12 after date of randomization
Migraine Intensity
migraine intensity, self-reported
Time frame: at baseline 4 weeks before randomization, week 2-6 after date of randomization, week 8-12 after date of randomization
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.