Comparison Of Efficacy Of Hydrocortisone And Methyl Prednisolone In Acute Severe Asthma

N/AUnknownNCT06171932

University of Karachi60 enrolled

Overview

COMPARISON OF EFFICACY OF HYDROCORTISONE AND METHYLPREDNISOLONE IN ACUTE SEVERE ASTHMA In this study Investigator will compare the efficacy of hydrocortisone and methyl prednisolone in acute severe asthma that will lead to final result and beneficial effects that will help in early resoloution of symptoms and help in preventing recurrence

investigator will compare the efficacy of hydrocortisone v/s methylprednisolone in management of patients presented with acute severe asthma in emergency. A local study was conducted in 2009, after that there is a big research gap exists at national level although international literature is available on the same but it can not be generalized to our population due to socio, geographic and economic differences so there is dire need to conduct this study this gives a strong rationale to implement in our settings

Study Type

OBSERVATIONAL

Enrollment

Conditions

Asthma Acute

Interventions

Methylprednisolone,DRUG

No intervention required

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Either Gender (18 to 50 years old) * Patient presenting to emergency department with acute severe asthma Exclusion Criteria: * Patients with critical illness or pregnant females. .Patient treated other than hydrocortisone and methylprednisolone. .Patients not willing to participate in study. * Life threatening asthma * Near fatal asthm

Locations (4)

Zia ud din hospital university

Karachi, Sindh, Pakistan

Zia ud din university hospital

Karachi, Sindh, Pakistan

Zia ud din university hospitals

Karachi, Sindh, Pakistan

Zia ud din university

Karachi, Sindh, Pakistan

Outcomes

Primary Outcomes

Spirometry

Above will be check on arrival of patient to Emergency and post Managment

Time frame: 24 hours

Blood pressures

Vital signs at initial presentation and post managment will be recorded Blood pressure in mm HG will be recorded

Time frame: 24 hours

Respiratory rate

Respiratory rate at arrival and post managment will be considered Respiratory rate in Breaths/min

Time frame: 24 hours

Heart rate

Heart rate beats/min will be checked

Time frame: 24 hours

PEAK EXPIRATORY FLOW RATE

it wil be checked on arrival and post managment in Peak Expiratory Flow rate (force expiratory volume in 1 second and force vital capacity )will be examined

Time frame: 24 hours

Data from ClinicalTrials.gov

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